Obsessive Compulsive Disorder in Children and Adolescents

ICD-10 code: F42.8

Obsessive-compulsive disorder (OCD) is part of a cluster of diagnoses called the obsessive-compulsive and related disorders. Obsessive-compulsive and related disorders are a group of psychiatric conditions that include:

  • Obsessive-compulsive disorder
  • Body dysmorphic disorder
  • Hoarding disorder
  • Trichotillomania
  • Excoriation (skin picking) disorder
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These disorders are characterized by the occurrence of repetitive behaviors, often called compulsions. Children with obsessive-compulsive disorder might engage in compulsive behaviors such as excessive washing, checking, arranging, or counting. Children with body dysmorphic disorder might engage in frequent checking of their appearance in the mirror, or excessive grooming-related behaviors. Children with hoarding disorder may engage in excessive acquiring of objects, combined with a strong need to save items. Children with trichotillomania engage in excessive hair pulling, and children with excoriation disorder engage in excessive skin picking.

In some cases, the obsessive-compulsive and related disorders are also characterized by intrusive, unwanted, or distressing thoughts, called obsessions, which come to mind again and again. Children with obsessive-compulsive disorder might have obsessive thoughts about dirt or germs, fears of something terrible happening, thoughts of harming others, fears of making mistakes, or distress about things being out of order. Children with body dysmorphic disorder have repetitive, negative thoughts about their own appearance. However, children with certain other obsessive-compulsive and related disorders (such as trichotillomania or excoriation disorder) often do not experience obsessive thoughts.

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What is obsessive compulsive disorder?

OCD is a psychiatric disorder that affects approximately 1 - 3% of children and adolescents. OCD is characterized by two main symptoms:

  • Obsessions, which are unwanted or intrusive thoughts, ideas, fears, or mental images that the child finds distressing.
  • Compulsions, which are repetitive behaviors that the child does in response to obsessions or fears.
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There are many different kinds of obsessions and compulsions. Some of the more common ones in children are:

  • Fears of dirt, germs, or contamination, often associated with compulsive washing or cleaning.
  • Fears of a catastrophic event, such as the death of a parent, often associated with compulsive checking or superstitious behaviors.
  • Excessive scruples or guilt, often associated with compulsive mental rituals (such as praying in a certain way) or reassurance-seeking from adults.
  • Excessive concern about order and symmetry, often associated with compulsive arranging or ordering.
  • Unwanted, frightening, or repugnant thoughts or mental images, often associated with compulsive mental rituals or repeating behaviors.
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Understanding Obsessive Compulsive Disorder

OCD severity can range from mild to debilitating. In severe cases, OCD can lead to inability to attend school or engage in family or recreational activities. Many children and adolescents with OCD also have other psychiatric conditions, most commonly anxiety disorders. A younger age of onset of OCD is associated with an increased likelihood of certain comorbid conditions, including anxiety and attention deficit-hyperactivity disorder.

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OCD is characterized by abnormalities of brain function which are thought to contribute to symptoms. In particular, evidence points to a hyperactive loop extending from the frontal cortex to the basal ganglia, which affects inhibition of thoughts and behaviors, modulation of emotion, and other aspects of the disorder. In addition, compulsive behavior and avoidance of feared situations are thought to contribute to the persistence of obsessive fears. OCD disorder has a genetic component, although having a genetic predisposition to OCD does not necessarily mean that someone will develop OCD.

In a small number of pediatric OCD cases, OCD symptoms may result from exposure to a subtype of streptococcal infection. In these cases, OCD onset is abrupt and accompanied by other symptoms, including a clear decline in handwriting and mathematical ability.

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How is obsessive compulsive disorder treated?

OCD is treatable. Published treatment guidelines for children and adolescents with OCD include those from the American Academy of Child and Adolescent Psychiatry and the National Institute for Clinical Excellence.

First Line Treatments

  • Cognitive-behavioral therapy consists of gradually exposing the child to feared objects, activities, or thoughts, while simultaneously refraining from compulsive behavior. CBT for pediatric OCD usually includes parent interventions, which help parents more effectively manage their child's behavior and reduce anxiety symptoms.
  • For moderate to severe OCD, antidepressant medications, which are thought to help by improving the amount of serotonin in the brain, are recommended as an adjunctive treatment for CBT. Specific first-line medications for pediatric OCD are selective serotonin reuptake inhibitors (SSRIs) including:
    • Sertraline
    • Fluvoxamine
    • Fluoxetine
    • Paroxetine

Other Effective Treatments

In cases of nonresponse to first-line treatment, alternative treatments with reasonable evidence of efficacy include:

  • Monotherapy with antidepressant medications such as clomipramine
  • Augmentation of SSRI medication with clomipramine
  • Combined CBT and SSRI treatment (note: this is the first-line treatment for moderate to severe pediatric OCD)

In addition, research suggests that the following treatments are promising:

  • Augmentation of SSRIs with clonazepam, atypical neuroleptic medications, or stimulant medications
  • Monotherapy with the glutamatergic medication riluzole
  • D-cycloserine augmentation of CBT

First Line Treatments

Other Effective Treatments

In cases of nonresponse to first-line treatment, alternative treatments with reasonable evidence of efficacy include:

In addition, research suggests that the following treatments are promising: